The National Science Foundation’s Software Development for Cyberinfrastructure (SDCI) program is dedicated to the development of widely redeployable software systems which advance the methods of research and education employed in a broad range of fields in science and engineering. SDCI directly addresses the software-centric issues laid out in NSF’s Cyberinfrastructure Vision for 21st Century Discovery, seeking to fund and promote the development of innovative software solutions to issues such as the management and analysis of extremely large collections of data, collaboration across disparate disciplines and institutions, and make the use of high performance computing systems both more productive and more accessible. SDCI addresses these issues through awards given across five software focus areas (HPC systems, digital data management, broadband and networking, middleware, and cybersecurity) as well as three cross-cutting issues in software development (sustainability, self-manageability, and energy efficiency).